Cargando…

Polymerase δ replicates both strands after homologous recombination-dependent fork restart

To maintain genetic stability DNA must be replicated only once and replication completed even when individual replication forks are inactivated. Because fork inactivation is common, the passive convergence of an adjacent fork is insufficient to rescue all inactive forks. Thus, eukaryotic cells have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miyabe, Izumi, Mizuno, Ken’Ichi, Keszthelyi, Andrea, Daigaku, Yasukazu, Skouteri, Meliti, Mohebi, Saed, Kunkel, Thomas A., Murray, Johanne M., Carr, Antony M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655445/ https://www.ncbi.nlm.nih.gov/pubmed/26436826 http://dx.doi.org/10.1038/nsmb.3100

Ejemplares similares

Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements
por: Mohebi, Saed, et al.
Publicado: (2015)

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats
por: Mizuno, Ken’Ichi, et al.
Publicado: (2012)

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved
por: Miyabe, Izumi, et al.
Publicado: (2011)

Optimisation of the Schizosaccharomyces pombe urg1 Expression System
por: Watson, Adam T., et al.
Publicado: (2013)

Characterisation of a stably integrated expression system for exogenous protein expression in DT40
por: Skouteri, Meliti, et al.
Publicado: (2017)

The extent of error-prone replication restart by homologous recombination is controlled by Exo1 and checkpoint proteins
por: Tsang, Ellen, et al.
Publicado: (2014)

A global profile of replicative polymerase usage
por: Daigaku, Yasukazu, et al.
Publicado: (2015)

Replication dynamics of recombination-dependent replication forks
por: Naiman, Karel, et al.
Publicado: (2021)

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
por: Shorrocks, Ann-Marie K., et al.
Publicado: (2021)

PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast
por: Daigaku, Yasukazu, et al.
Publicado: (2017)

Preserving replication fork integrity and competence via the homologous recombination pathway
por: Ait Saada, Anissia, et al.
Publicado: (2018)

The FLIP-FIGNL1 complex regulates the dissociation of RAD51/DMC1 in homologous recombination and replication fork restart
por: Zhang, Qianting, et al.
Publicado: (2023)

Metnase promotes restart and repair of stalled and collapsed replication forks
por: De Haro, Leyma P., et al.
Publicado: (2010)

MUS81-EME2 Promotes Replication Fork Restart
por: Pepe, Alessandra, et al.
Publicado: (2014)

UV stalled replication forks restart by re-priming in human fibroblasts
por: Elvers, Ingegerd, et al.
Publicado: (2011)

Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
por: Pomerantz, Richard T., et al.
Publicado: (2010)

Checkpoint-dependent RNR induction promotes fork restart after replicative stress
por: Morafraile, Esther C., et al.
Publicado: (2015)

DNA2 drives processing and restart of reversed replication forks in human cells
por: Thangavel, Saravanabhavan, et al.
Publicado: (2015)

Degradation of Mrc1 promotes recombination-mediated restart of stalled replication forks
por: Chaudhury, Indrajit, et al.
Publicado: (2017)

Sequential role of RAD51 paralog complexes in replication fork remodeling and restart
por: Berti, Matteo, et al.
Publicado: (2020)

Restarted replication forks are error-prone and cause CAG repeat expansions and contractions
por: Gold, Michaela A., et al.
Publicado: (2021)

Homologous Recombination: To Fork and Beyond
por: Prado, Félix
Publicado: (2018)

Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells
por: Batenburg, Nicole L, et al.
Publicado: (2021)

The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination
por: Nickoloff, Jac A., et al.
Publicado: (2021)

RIF1 promotes replication fork protection and efficient restart to maintain genome stability
por: Mukherjee, Chirantani, et al.
Publicado: (2019)

Homologous Recombination as a Replication Fork Escort: Fork-Protection and Recovery
por: Costes, Audrey, et al.
Publicado: (2012)

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
por: Berti, Matteo, et al.
Publicado: (2013)

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
por: Somyajit, Kumar, et al.
Publicado: (2015)

Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart
por: Somyajit, Kumar, et al.
Publicado: (2020)

Single strand transposition at the host replication fork
por: Lavatine, Laure, et al.
Publicado: (2016)

Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse
por: Nguyen, Michael O, et al.
Publicado: (2015)

SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
por: Pedersen, Ida Benedikte, et al.
Publicado: (2017)

DNA Helicase-SSB Interactions Critical to the Regression and Restart of Stalled DNA Replication Forks in Escherichia coli
por: Bianco, Piero R.
Publicado: (2020)

The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast
por: Wong, Io Nam, et al.
Publicado: (2019)

A fork in the road: Where homologous recombination and stalled replication fork protection part ways
por: Tye, Stephanie, et al.
Publicado: (2021)

The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
por: Al-Minawi, Ali Z., et al.
Publicado: (2009)

Motif WFYY of human PrimPol is crucial to stabilize the incoming 3′-nucleotide during replication fork restart
por: Calvo, Patricia A, et al.
Publicado: (2021)

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
por: Zhou, Zhi-Xiong, et al.
Publicado: (2019)

XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
por: Eckelmann, Bradley J, et al.
Publicado: (2020)

MT1-MMP-dependent ECM processing regulates laminB1 stability and mediates replication fork restart
por: Thakur, Varsha, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4k2gmlic7sc7ahbl5s81jqnfqe