Differential basal-to-apical accessibility of lamin A/C epitopes in the nuclear lamina regulated by changes in cytoskeletal tension

Nuclear lamins play central roles at the intersection between cytoplasmic signalling and nuclear events. Here, we show that at least two N- and C-terminal lamin epitopes are not accessible at the basal side of the nuclear envelope under environmental conditions known to upregulate cell contractility...

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Detalles Bibliográficos
Autores principales: Ihalainen, Teemu O., Aires, Lina, Herzog, Florian A., Schwartlander, Ruth, Moeller, Jens, Vogel, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655446/
https://www.ncbi.nlm.nih.gov/pubmed/26301768
http://dx.doi.org/10.1038/nmat4389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655446/
https://www.ncbi.nlm.nih.gov/pubmed/26301768
http://dx.doi.org/10.1038/nmat4389

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