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Differential basal-to-apical accessibility of lamin A/C epitopes in the nuclear lamina regulated by changes in cytoskeletal tension
Nuclear lamins play central roles at the intersection between cytoplasmic signalling and nuclear events. Here, we show that at least two N- and C-terminal lamin epitopes are not accessible at the basal side of the nuclear envelope under environmental conditions known to upregulate cell contractility...
Autores principales: | Ihalainen, Teemu O., Aires, Lina, Herzog, Florian A., Schwartlander, Ruth, Moeller, Jens, Vogel, Viola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655446/ https://www.ncbi.nlm.nih.gov/pubmed/26301768 http://dx.doi.org/10.1038/nmat4389 |
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