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Gene methylation of human ovarian carcinoma stromal progenitor cells promotes tumorigenesis

BACKGROUND: This study aimed to investigate whether the DNA methylation of human ovarian carcinoma stromal progenitor cells (OCSPCs) could promote the tumorigenesis of ovarian carcinoma. METHODS: OCSPCs were first isolated from fresh tumor tissues and ascites of ovarian cancer patients. In vivo and...

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Detalles Bibliográficos
Autores principales: Ho, Chih-Ming, Shih, Daniel Tzu-bi, Hsiao, Chih-Chiang, Huang, Shih-Hung, Chang, Shwu-Fen, Cheng, Wen-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655458/
https://www.ncbi.nlm.nih.gov/pubmed/26597084
http://dx.doi.org/10.1186/s12967-015-0722-7