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Structural biology and chemistry of protein arginine methyltransferases
Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other substrates, and can be divided into three subgroups, based on the methylation pattern of the reaction product (monomethylation, symmetrical or asymmetrical dimethylation). Here,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655611/ https://www.ncbi.nlm.nih.gov/pubmed/26693001 http://dx.doi.org/10.1039/c4md00269e |