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Structural biology and chemistry of protein arginine methyltransferases

Protein arginine methyltransferases (PRMTs), an emerging target class in drug discovery, can methylate histones and other substrates, and can be divided into three subgroups, based on the methylation pattern of the reaction product (monomethylation, symmetrical or asymmetrical dimethylation). Here,...

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Detalles Bibliográficos
Autores principales:	Schapira, Matthieu, Ferreira de Freitas, Renato
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2014
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655611/ https://www.ncbi.nlm.nih.gov/pubmed/26693001 http://dx.doi.org/10.1039/c4md00269e

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