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Determination of Vitamin D Serum Levels and Status of the C3435T Polymorphism of Multidrug Resistance 1 Gene in Southeastern Iranian Patients with Ulcerative Colitis

BACKGROUND Ulcerative colitis (UC) is a multi-factorial autoimmune disease. P-glycoprotein is encoded by the multidrug resistance 1 (MDR1) gene. The C3435T polymorphism in the MDR1 gene is correlated with low P-glycoprotein expression. Additionally, vitamin D has regulatory effects on the immune sys...

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Detalles Bibliográficos
Autores principales: Mohammadi, Mojgan, Zahedi, Mohammad Javad, Nikpoor, Amin Reza, Nazem, Mehdi, Khazaeli, Payam, Hayatbakhsh, Mohammad Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Association of Gastroerterology and Hepatology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655846/
https://www.ncbi.nlm.nih.gov/pubmed/26609354