Heterozygous Deletion of α-Neurexin I or α-Neurexin II Results in Behaviors Relevant to Autism and Schizophrenia

The neurexins are a family of presynaptic cell adhesion molecules. Human genetic studies have found heterozygous deletions affecting NRXN1 and NRXN2, encoding α-neurexin I (Nrxn1α) and α-neurexin II (Nrxn2α), in individuals with autism spectrum disorders and schizophrenia. However, the link between...

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Detalles Bibliográficos
Autores principales: Dachtler, James, Ivorra, Jose L., Rowland, Tessa E., Lever, Colin, Rodgers, R. John, Clapcote, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Psychological Association 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655861/
https://www.ncbi.nlm.nih.gov/pubmed/26595880
http://dx.doi.org/10.1037/bne0000108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655861/
https://www.ncbi.nlm.nih.gov/pubmed/26595880
http://dx.doi.org/10.1037/bne0000108

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