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Causative factors for formation of toxic islet amyloid polypeptide oligomer in type 2 diabetes mellitus
Human islet amyloid polypeptide (h-IAPP) is a peptide hormone that is synthesized and cosecreted with insulin from insulin-secreting pancreatic β-cells. Recently, h-IAPP was proposed to be the main component responsible for the cytotoxic pancreatic amyloid deposits in patients with type 2 diabetes m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655906/ https://www.ncbi.nlm.nih.gov/pubmed/26604727 http://dx.doi.org/10.2147/CIA.S95297 |