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A new Agkistrodon halys venom-purified protein C activator prevents myocardial fibrosis in diabetic rats

AIM: To assess the effects of protein C activator (PCA) from Agkistrodon halys snake venom on cardiac fibrosis in streptozotocin (STZ) induced diabetic rat model, and investigate the mechanisms of its action. METHODS: PCA was identified by one-dimensional reversed phase liquid chromatography – mass...

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Detalles Bibliográficos
Autores principales: Li, Shu, Hong, Yun, Jin, Xin, Zhang, Genbao, Hu, Zaichang, Nie, Liuwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655929/
https://www.ncbi.nlm.nih.gov/pubmed/26526881
http://dx.doi.org/10.3325/cmj.2015.56.439