Cargando…

Novel 24-h ovine model of brain death to study the profile of the endothelin axis during cardiopulmonary injury

BACKGROUND: Upregulation of the endothelin axis has been observed in pulmonary tissue after brain death, contributing to primary graft dysfunction and ischaemia reperfusion injury. The current study aimed to develop a novel, 24-h, clinically relevant, ovine model of brain death to investigate the pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Watts, Ryan P., Bilska, Izabela, Diab, Sara, Dunster, Kimble R., Bulmer, Andrew C., Barnett, Adrian G., Fraser, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656265/
https://www.ncbi.nlm.nih.gov/pubmed/26596583
http://dx.doi.org/10.1186/s40635-015-0067-9