Exendin-4 attenuates adverse cardiac remodelling in streptozocin-induced diabetes via specific actions on infiltrating macrophages

In addition to its' established metabolic and cardioprotective effects, glucagon-like peptide-1 (GLP-1) reduces post-infarction heart failure via preferential actions on the extracellular matrix (ECM). Here, we investigated whether the GLP-1 mimetic, exendin-4, modulates cardiac remodelling in...

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Detalles Bibliográficos
Autores principales: Tate, Mitchel, Robinson, Emma, Green, Brian D., McDermott, Barbara J., Grieve, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656717/
https://www.ncbi.nlm.nih.gov/pubmed/26597728
http://dx.doi.org/10.1007/s00395-015-0518-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656717/
https://www.ncbi.nlm.nih.gov/pubmed/26597728
http://dx.doi.org/10.1007/s00395-015-0518-1

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