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Exendin-4 attenuates adverse cardiac remodelling in streptozocin-induced diabetes via specific actions on infiltrating macrophages
In addition to its' established metabolic and cardioprotective effects, glucagon-like peptide-1 (GLP-1) reduces post-infarction heart failure via preferential actions on the extracellular matrix (ECM). Here, we investigated whether the GLP-1 mimetic, exendin-4, modulates cardiac remodelling in...
Autores principales: | Tate, Mitchel, Robinson, Emma, Green, Brian D., McDermott, Barbara J., Grieve, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656717/ https://www.ncbi.nlm.nih.gov/pubmed/26597728 http://dx.doi.org/10.1007/s00395-015-0518-1 |
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