An Autogenously Regulated Expression System for Gene Therapeutic Ocular Applications

The future of treating inherited and acquired genetic diseases will be defined by our ability to introduce transgenes into cells and restore normal physiology. Here we describe an autogenous transgene regulatory system (ARES), based on the bacterial lac repressor, and demonstrate its utility for con...

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Detalles Bibliográficos
Autores principales: Sochor, Matthew A., Vasireddy, Vidyullatha, Drivas, Theodore G., Wojno, Adam, Doung, Thu, Shpylchak, Ivan, Bennicelli, Jeannette, Chung, Daniel, Bennett, Jean, Lewis, Mitchell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656984/
https://www.ncbi.nlm.nih.gov/pubmed/26597678
http://dx.doi.org/10.1038/srep17105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656984/
https://www.ncbi.nlm.nih.gov/pubmed/26597678
http://dx.doi.org/10.1038/srep17105

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