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RNA-based, transient modulation of gene expression in human haematopoietic stem and progenitor cells

Modulation of gene expression is a useful tool to study the biology of haematopoietic stem and progenitor cells (HSPCs) and might also be instrumental to expand these cells for therapeutic approaches. Most of the studies so far have employed stable gene modification by viral vectors that are burdens...

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Detalles Bibliográficos
Autores principales: Diener, Yvonne, Jurk, Marion, Kandil, Britta, Choi, Yeong-Hoon, Wild, Stefan, Bissels, Ute, Bosio, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657003/
https://www.ncbi.nlm.nih.gov/pubmed/26599627
http://dx.doi.org/10.1038/srep17184