PRL-3 activates mTORC1 in Cancer Progression

PRL-3, a metastasis-associated phosphatase, is known to exert its oncogenic functions through activation of PI3K/Akt, which is a key regulator of the rapamycin-sensitive mTOR complex 1 (mTORC1), but a coherent link between PRL-3 and activation of mTOR has not yet been formally demonstrated. We repor...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Zu, Al-aidaroos, Abdul Qader Omer, Park, Jung Eun, Yuen, Hiu Fung, Zhang, Shu Dong, Gupta, Abhishek, Lin, Youbin, Shen, Han-Ming, Zeng, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657013/
https://www.ncbi.nlm.nih.gov/pubmed/26597054
http://dx.doi.org/10.1038/srep17046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657013/
https://www.ncbi.nlm.nih.gov/pubmed/26597054
http://dx.doi.org/10.1038/srep17046

Ejemplares similares