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PRL-3 activates mTORC1 in Cancer Progression

PRL-3, a metastasis-associated phosphatase, is known to exert its oncogenic functions through activation of PI3K/Akt, which is a key regulator of the rapamycin-sensitive mTOR complex 1 (mTORC1), but a coherent link between PRL-3 and activation of mTOR has not yet been formally demonstrated. We repor...

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Detalles Bibliográficos
Autores principales:	Ye, Zu, Al-aidaroos, Abdul Qader Omer, Park, Jung Eun, Yuen, Hiu Fung, Zhang, Shu Dong, Gupta, Abhishek, Lin, Youbin, Shen, Han-Ming, Zeng, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657013/ https://www.ncbi.nlm.nih.gov/pubmed/26597054 http://dx.doi.org/10.1038/srep17046

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