Loss of Polo ameliorates APP-induced Alzheimer’s disease-like symptoms in Drosophila

The amyloid precursor protein (APP) has been implicated in the pathogenesis of Alzheimer’s disease (AD). Despite extensive studies, little is known about the regulation of APP’s functions in vivo. Here we report that expression of human APP in Drosophila, in the same temporal-spatial pattern as its...

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Detalles Bibliográficos
Autores principales: Peng, Fei, Zhao, Yu, Huang, Xirui, Chen, Changyan, Sun, Lili, Zhuang, Luming, Xue, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657023/
https://www.ncbi.nlm.nih.gov/pubmed/26597721
http://dx.doi.org/10.1038/srep16816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657023/
https://www.ncbi.nlm.nih.gov/pubmed/26597721
http://dx.doi.org/10.1038/srep16816

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