Structure of the Human Factor VIII C2 Domain in Complex with the 3E6 Inhibitory Antibody

Blood coagulation factor VIII is a glycoprotein cofactor that is essential for the intrinsic pathway of the blood coagulation cascade. Inhibitory antibodies arise either spontaneously or in response to therapeutic infusion of functional factor VIII into hemophilia A patients, many of which are speci...

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Detalles Bibliográficos
Autores principales: Wuerth, Michelle E., Cragerud, Rebecca K., Clint Spiegel, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657047/
https://www.ncbi.nlm.nih.gov/pubmed/26598467
http://dx.doi.org/10.1038/srep17216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657047/
https://www.ncbi.nlm.nih.gov/pubmed/26598467
http://dx.doi.org/10.1038/srep17216

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