Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression

In vertebrates, the inner ear arises from the otic placode, a thickened swathe of ectoderm that invaginates to form the otic vesicle. We report that histone demethylase KDM4B is dynamically expressed during early stages of chick inner ear formation. A loss of KDM4B results in defective invagination...

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Detalles Bibliográficos
Autores principales: Uribe, Rosa A., Buzzi, Ailín L., Bronner, Marianne E., Strobl-Mazzulla, Pablo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657164/
https://www.ncbi.nlm.nih.gov/pubmed/26598618
http://dx.doi.org/10.1083/jcb.201503071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657164/
https://www.ncbi.nlm.nih.gov/pubmed/26598618
http://dx.doi.org/10.1083/jcb.201503071

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