Cargando…
Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression
In vertebrates, the inner ear arises from the otic placode, a thickened swathe of ectoderm that invaginates to form the otic vesicle. We report that histone demethylase KDM4B is dynamically expressed during early stages of chick inner ear formation. A loss of KDM4B results in defective invagination...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657164/ https://www.ncbi.nlm.nih.gov/pubmed/26598618 http://dx.doi.org/10.1083/jcb.201503071 |