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Amelioration of Japanese encephalitis by blockage of 4-1BB signaling is coupled to divergent enhancement of type I/II IFN responses and Ly-6C(hi) monocyte differentiation

BACKGROUND: Japanese encephalitis (JE), a neuroinflammation caused by zoonotic JE virus, is the major cause of viral encephalitis worldwide and poses an increasing threat to global health and welfare. To date, however, there has been no report describing the regulation of JE progression using immuno...

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Detalles Bibliográficos
Autores principales: Kim, Seong Bum, Choi, Jin Young, Kim, Jin Hyoung, Uyangaa, Erdenebelig, Patil, Ajit Mahadev, Park, Sang-Youel, Lee, John Hwa, Kim, Koanhoi, Han, Young Woo, Eo, Seong Kug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657197/
https://www.ncbi.nlm.nih.gov/pubmed/26597582
http://dx.doi.org/10.1186/s12974-015-0438-x