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The autophagic response to polystyrene nanoparticles is mediated by transcription factor EB and depends on surface charge

BACKGROUND: A number of engineered nanoparticles induce autophagy, the main catabolic pathway that regulates bulk degradation of cytoplasmic material by the lysosomes. Depending on the specific physico-chemical properties of the nanomaterial, however, nanoparticle-induced autophagy may have differen...

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Detalles Bibliográficos
Autores principales: Song, Wensi, Popp, Lauren, Yang, Justin, Kumar, Ayushi, Gangoli, Varun Shenoy, Segatori, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657241/
https://www.ncbi.nlm.nih.gov/pubmed/26596266
http://dx.doi.org/10.1186/s12951-015-0149-6