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The autophagic response to polystyrene nanoparticles is mediated by transcription factor EB and depends on surface charge
BACKGROUND: A number of engineered nanoparticles induce autophagy, the main catabolic pathway that regulates bulk degradation of cytoplasmic material by the lysosomes. Depending on the specific physico-chemical properties of the nanomaterial, however, nanoparticle-induced autophagy may have differen...
Autores principales: | Song, Wensi, Popp, Lauren, Yang, Justin, Kumar, Ayushi, Gangoli, Varun Shenoy, Segatori, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657241/ https://www.ncbi.nlm.nih.gov/pubmed/26596266 http://dx.doi.org/10.1186/s12951-015-0149-6 |
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