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Resource constrained flux balance analysis predicts selective pressure on the global structure of metabolic networks
BACKGROUND: A universal feature of metabolic networks is their hourglass or bow-tie structure on cellular level. This architecture reflects the conversion of multiple input nutrients into multiple biomass components via a small set of precursor metabolites. However, it is yet unclear to what extent...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657269/ https://www.ncbi.nlm.nih.gov/pubmed/26597226 http://dx.doi.org/10.1186/s12918-015-0232-5 |