Phosphatidylinositol- 3-kinase inhibitor induces chemosensitivity to a novel derivative of doxorubicin, AD198 chemotherapy in human bladder cancer cells in vitro

BACKGROUND: Doxorubicin (Dox) is widely used to treat progressed bladder cancer after transurethral resection. The use of Dox-chemotherapy has been limited due to induced drug resistance and cumulative cardiotoxic effects. N-benzyladriamycin-14-valerate (AD198), a novel derivative of Dox, has a pote...

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Detalles Bibliográficos
Autores principales: Smolensky, Dmitriy, Rathore, Kusum, Cekanova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657321/
https://www.ncbi.nlm.nih.gov/pubmed/26597249
http://dx.doi.org/10.1186/s12885-015-1930-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657321/
https://www.ncbi.nlm.nih.gov/pubmed/26597249
http://dx.doi.org/10.1186/s12885-015-1930-5

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