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Neo-epitopes emerging in the degenerative hippocampal granules of aged mice can be recognized by natural IgM auto-antibodies

BACKGROUND: Degenerative granular structures appear progressively with age in the hippocampus of most mouse strains. We recently reported that these granules contain a neo-epitope that is recognised by IgM antibodies present as contaminants in many commercial antibodies obtained from mouse ascites a...

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Detalles Bibliográficos
Autores principales: Manich, Gemma, Augé, Elisabet, Cabezón, Itsaso, Pallàs, Mercè, Vilaplana, Jordi, Pelegrí, Carme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657344/
https://www.ncbi.nlm.nih.gov/pubmed/26604974
http://dx.doi.org/10.1186/s12979-015-0050-z