Cargando…

Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells

BACKGROUND: One of the challenging problems of current radio-chemotherapy is recurrence and metastasis of cancer cells that survive initial treatment. We propose that one of the unwanted effects of radiochemotherapy is the release from damaged (“leaky”) cells of nucleotides such as ATP and UTP that...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Gabriela, Glaser, Talita, Lameu, Claudiana, Abdelbaset-Ismail, Ahmed, Sellers, Zachariah Payne, Moniuszko, Marcin, Ulrich, Henning, Ratajczak, Mariusz Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657356/
https://www.ncbi.nlm.nih.gov/pubmed/26597723
http://dx.doi.org/10.1186/s12943-015-0469-z