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Minnelide effectively eliminates CD133(+) side population in pancreatic cancer

BACKGROUND: Pancreatic Ductal Adenocarcinoma (PDAC) is a devastating disease hallmarked by limited patient survival. Resistance to chemotherapy, a major cause of treatment failure in PDAC patients, is often attributed to Cancer Stem Cells (CSCs). Pancreatic CSCs are a small subset of quiescent cells...

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Detalles Bibliográficos
Autores principales: Nomura, Alice, McGinn, Olivia, Dudeja, Vikas, Sangwan, Veena, Saluja, Ashok K., Banerjee, Sulagna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657383/
https://www.ncbi.nlm.nih.gov/pubmed/26597727
http://dx.doi.org/10.1186/s12943-015-0470-6