Cargando…
Minnelide effectively eliminates CD133(+) side population in pancreatic cancer
BACKGROUND: Pancreatic Ductal Adenocarcinoma (PDAC) is a devastating disease hallmarked by limited patient survival. Resistance to chemotherapy, a major cause of treatment failure in PDAC patients, is often attributed to Cancer Stem Cells (CSCs). Pancreatic CSCs are a small subset of quiescent cells...
Autores principales: | Nomura, Alice, McGinn, Olivia, Dudeja, Vikas, Sangwan, Veena, Saluja, Ashok K., Banerjee, Sulagna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657383/ https://www.ncbi.nlm.nih.gov/pubmed/26597727 http://dx.doi.org/10.1186/s12943-015-0470-6 |
Ejemplares similares
-
Microenvironment mediated alterations to metabolic pathways confer increased chemo-resistance in CD133(+) tumor initiating cells
por: Nomura, Alice, et al.
Publicado: (2016) -
CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer
por: Nomura, Alice, et al.
Publicado: (2015) -
Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia
por: Giri, Bhuwan, et al.
Publicado: (2019) -
Downregulation of Sp1 by Minnelide leads to decrease in HSP70 and decrease in tumor burden of gastric cancer
por: Arora, Nivedita, et al.
Publicado: (2017) -
Minnelide: A Novel Therapeutic That Promotes Apoptosis in Non-Small Cell Lung Carcinoma In Vivo
por: Rousalova, Ilona, et al.
Publicado: (2013)