DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

The detection of nucleic acids by the innate immune system is an essential host response during viral infection. In recent years, a number of immune sensors capable of recognizing cytosolic DNA have been identified and include the PYHIN family members AIM2, IFI16, and p204 as well as the enzyme, cGA...

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Detalles Bibliográficos
Autores principales: Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657478/
https://www.ncbi.nlm.nih.gov/pubmed/25627810
http://dx.doi.org/10.1002/glia.22786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657478/
https://www.ncbi.nlm.nih.gov/pubmed/25627810
http://dx.doi.org/10.1002/glia.22786

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