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Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis

Aims: One of the cancer hallmarks is mitochondrial dysfunction associated with oxidative stress. Among the first line of defense against oxidative stress is the dismutation of superoxide radicals, which in the mitochondria is carried out by manganese superoxide dismutase (MnSOD). Accordingly, carcin...

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Detalles Bibliográficos
Autores principales: Konzack, Anja, Jakupovic, Mirza, Kubaichuk, Kateryna, Görlach, Agnes, Dombrowski, Frank, Miinalainen, Ilkka, Sormunen, Raija, Kietzmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657515/
https://www.ncbi.nlm.nih.gov/pubmed/26422659
http://dx.doi.org/10.1089/ars.2015.6318