Notch1 and Notch2 in Podocytes Play Differential Roles During Diabetic Nephropathy Development

Notch pathway activation in podocytes has been shown to play an important role in diabetic kidney disease (DKD) development; however, the receptors and ligands involved in the process have not been identified. Here, we report that conditional deletion of Notch1 in podocytes using NPHS2(cre)Notch1(fl...

Descripción completa

Detalles Bibliográficos
Autores principales: Sweetwyne, Mariya T., Gruenwald, Antje, Niranjan, Thiruvur, Nishinakamura, Ryuichi, Strobl, Lothar J., Susztak, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657584/
https://www.ncbi.nlm.nih.gov/pubmed/26293507
http://dx.doi.org/10.2337/db15-0260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657584/
https://www.ncbi.nlm.nih.gov/pubmed/26293507
http://dx.doi.org/10.2337/db15-0260

Ejemplares similares