Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation

The generation of diverse neuronal subtypes involves specification of neural progenitors and, subsequently, postmitotic neuronal differentiation, a relatively poorly understood process. Here, we describe a mechanism whereby the neurotrophic factor NGF and the transcription factor Runx1 coordinate po...

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Detalles Bibliográficos
Autores principales: Huang, Siyi, O'Donovan, Kevin J, Turner, Eric E, Zhong, Jian, Ginty, David D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657622/
https://www.ncbi.nlm.nih.gov/pubmed/26418744
http://dx.doi.org/10.7554/eLife.10874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657622/
https://www.ncbi.nlm.nih.gov/pubmed/26418744
http://dx.doi.org/10.7554/eLife.10874

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