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Extrinsic and intrinsic signals converge on the Runx1/CBFβ transcription factor for nonpeptidergic nociceptor maturation
The generation of diverse neuronal subtypes involves specification of neural progenitors and, subsequently, postmitotic neuronal differentiation, a relatively poorly understood process. Here, we describe a mechanism whereby the neurotrophic factor NGF and the transcription factor Runx1 coordinate po...
Autores principales: | Huang, Siyi, O'Donovan, Kevin J, Turner, Eric E, Zhong, Jian, Ginty, David D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657622/ https://www.ncbi.nlm.nih.gov/pubmed/26418744 http://dx.doi.org/10.7554/eLife.10874 |
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