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Therapeutic Intervention in Multiple Sclerosis with Alpha B-Crystallin: A Randomized Controlled Phase IIa Trial

As a molecular chaperone and activator of Toll-like receptor 2-mediated protective responses by microglia and macrophages, the small heat shock protein alpha B-crystallin (HspB5) exerts therapeutic effects in different animal models for neuroinflammation, including the model for multiple sclerosis (...

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Detalles Bibliográficos
Autores principales: van Noort, Johannes M., Bsibsi, Malika, Nacken, Peter J., Verbeek, Richard, Venneker, Edna H.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657879/
https://www.ncbi.nlm.nih.gov/pubmed/26599332
http://dx.doi.org/10.1371/journal.pone.0143366