Design, Synthesis and In Vitro Activity of Anticancer Styrylquinolines. The p53 Independent Mechanism of Action

A group of styrylquinolines were synthesized and tested for their anti-proliferative activity. Anti-proliferative activity was evaluated against the human colon carcinoma cell lines that had a normal expression of the p53 protein (HCT116 p53(+/+)) and mutants with a disabled TP53 gene (HCT116 p53(-/...

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Detalles Bibliográficos
Autores principales: Mrozek-Wilczkiewicz, Anna, Spaczynska, Ewelina, Malarz, Katarzyna, Cieslik, Wioleta, Rams-Baron, Marzena, Kryštof, Vladimír, Musiol, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657899/
https://www.ncbi.nlm.nih.gov/pubmed/26599982
http://dx.doi.org/10.1371/journal.pone.0142678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657899/
https://www.ncbi.nlm.nih.gov/pubmed/26599982
http://dx.doi.org/10.1371/journal.pone.0142678

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