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A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA

Placental malaria caused by Plasmodium falciparum is a major cause of mortality and severe morbidity. Clinical testing of a soluble protein-based vaccine containing the parasite ligand, VAR2CSA, has been initiated. VAR2CSA binds to the human receptor chondroitin sulphate A (CSA) and is responsible f...

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Detalles Bibliográficos
Autores principales: Thrane, Susan, Janitzek, Christoph M., Agerbæk, Mette Ø., Ditlev, Sisse B., Resende, Mafalda, Nielsen, Morten A., Theander, Thor G., Salanti, Ali, Sander, Adam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657905/
https://www.ncbi.nlm.nih.gov/pubmed/26599509
http://dx.doi.org/10.1371/journal.pone.0143071