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A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA
Placental malaria caused by Plasmodium falciparum is a major cause of mortality and severe morbidity. Clinical testing of a soluble protein-based vaccine containing the parasite ligand, VAR2CSA, has been initiated. VAR2CSA binds to the human receptor chondroitin sulphate A (CSA) and is responsible f...
Autores principales: | Thrane, Susan, Janitzek, Christoph M., Agerbæk, Mette Ø., Ditlev, Sisse B., Resende, Mafalda, Nielsen, Morten A., Theander, Thor G., Salanti, Ali, Sander, Adam F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657905/ https://www.ncbi.nlm.nih.gov/pubmed/26599509 http://dx.doi.org/10.1371/journal.pone.0143071 |
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