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Increased Notch Signaling Enhances Radioresistance of Malignant Stromal Cells Induced by Glioma Stem/ Progenitor Cells

BACKGROUND: Host malignant stromal cells induced by glioma stem/progenitor cells were revealed to be more radiation-resistant than the glioma stem/progenitor cells themselves after malignant transformation in nude mice. However, the mechanism underlying this phenomenon remains unclear. METHODS: Mali...

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Detalles Bibliográficos
Autores principales: Shen, Yuntian, Chen, Hua, Zhang, Jinshi, Chen, Yanming, Wang, Mengyao, Ma, Jiawei, Hong, Lei, Liu, Ning, Fan, Qiuhong, Lu, Xueguan, Tian, Ye, Wang, Aidong, Dong, Jun, Lan, Qing, Huang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657951/
https://www.ncbi.nlm.nih.gov/pubmed/26599017
http://dx.doi.org/10.1371/journal.pone.0142594