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Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice

BACKGROUND AND AIMS: Glycoprotein nonmetastatic melanoma B (Gpnmb), a transmembrane glycoprotein that is expressed in macrophages, negatively regulates inflammation. We have reported that Gpnmb is strongly expressed in the livers of rats fed a choline-deficient, L-amino acid-defined (CDAA) diet. How...

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Detalles Bibliográficos
Autores principales: Kumagai, Kotaro, Tabu, Kazuaki, Sasaki, Fumisato, Takami, Yoichiro, Morinaga, Yuko, Mawatari, Seiichi, Hashimoto, Shinichi, Tanoue, Shiroh, Kanmura, Shuji, Tamai, Tsutomu, Moriuchi, Akihiro, Uto, Hirofumi, Tsubouchi, Hirohito, Ido, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657955/
https://www.ncbi.nlm.nih.gov/pubmed/26599547
http://dx.doi.org/10.1371/journal.pone.0143413