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Supplementation of Magnolol Attenuates Skeletal Muscle Atrophy in Bladder Cancer-Bearing Mice Undergoing Chemotherapy via Suppression of FoxO3 Activation and Induction of IGF-1

Skeletal muscle atrophy, the most prominent phenotypic feature of cancer cachexia, is often observed in cancer patients undergoing chemotherapy. Magnolol (M) extracted from Magnolia officinalis exhibits several pharmacological effects including anti-inflammatory and anticancer activities. In this st...

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Detalles Bibliográficos
Autores principales: Chen, Meng-Chuan, Chen, Yen-Lin, Lee, Chi-Feng, Hung, Chih-Huang, Chou, Tz-Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657971/
https://www.ncbi.nlm.nih.gov/pubmed/26600425
http://dx.doi.org/10.1371/journal.pone.0143594