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Development of an Aquaporin-4 Orthogonal Array of Particle-Based ELISA for Neuromyelitis Optica Autoantibodies Detection

Serological markers of Nuromyelitis Optica (NMO), an autoimmune disorder of the central nervous system, are autoantibodies targeting the astrocytic water channel aquaporin-4 (AQP4). We have previously demonstrated that the main epitopes for these autoantibodies (AQP4-IgG) are generated by the supram...

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Detalles Bibliográficos
Autores principales: Pisani, Francesco, Settanni, Paolo, Rosito, Stefania, Mola, Maria Grazia, Iorio, Raffaele, Tortorella, Carla, Ruggieri, Maddalena, Trojano, Maria, Svelto, Maria, Frigeri, Antonio, Nicchia, Grazia Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658006/
https://www.ncbi.nlm.nih.gov/pubmed/26599905
http://dx.doi.org/10.1371/journal.pone.0143679