A Jump-from-Cavity Pyrophosphate Ion Release Assisted by a Key Lysine Residue in T7 RNA Polymerase Transcription Elongation

Pyrophosphate ion (PPi) release during transcription elongation is a signature step in each nucleotide addition cycle. The kinetics and energetics of the process as well as how it proceeds with substantial conformational changes of the polymerase complex determine the mechano-chemical coupling mecha...

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Detalles Bibliográficos
Autores principales: Da, Lin-Tai, E, Chao, Duan, Baogen, Zhang, Chuanbiao, Zhou, Xin, Yu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658072/
https://www.ncbi.nlm.nih.gov/pubmed/26599007
http://dx.doi.org/10.1371/journal.pcbi.1004624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658072/
https://www.ncbi.nlm.nih.gov/pubmed/26599007
http://dx.doi.org/10.1371/journal.pcbi.1004624

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