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Methacholine-Induced Variations in Airway Volume and the Slope of the Alveolar Capnogram Are Distinctly Associated with Airflow Limitation and Airway Closure

Mechanisms driving alteration of lung function in response to inhalation of a methacholine aerosol are incompletely understood. To explore to what extent large and small airways contribute to airflow limitation and airway closure in this context, volumetric capnography was performed before (n = 93)...

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Detalles Bibliográficos
Autores principales: Plantier, Laurent, Marchand-Adam, Sylvain, Boyer, Laurent, Taillé, Camille, Delclaux, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658077/
https://www.ncbi.nlm.nih.gov/pubmed/26599006
http://dx.doi.org/10.1371/journal.pone.0143550