Cargando…

Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity

Exposure to chronic stress is a risk factor for cognitive decline and psychopathology in genetically predisposed individuals. Preliminary evidence in humans suggests that mineralocorticoid receptors (MRs) may confer resilience to these stress-related changes. We specifically tested this idea using a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanatsou, Sofia, Fearey, Brenna C., Kuil, Laura E., Lucassen, Paul J., Harris, Anjanette P., Seckl, Jonathan R., Krugers, Harm, Joels, Marian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658081/
https://www.ncbi.nlm.nih.gov/pubmed/26600250
http://dx.doi.org/10.1371/journal.pone.0142012