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Overexpression of Mineralocorticoid Receptors Partially Prevents Chronic Stress-Induced Reductions in Hippocampal Memory and Structural Plasticity
Exposure to chronic stress is a risk factor for cognitive decline and psychopathology in genetically predisposed individuals. Preliminary evidence in humans suggests that mineralocorticoid receptors (MRs) may confer resilience to these stress-related changes. We specifically tested this idea using a...
Autores principales: | Kanatsou, Sofia, Fearey, Brenna C., Kuil, Laura E., Lucassen, Paul J., Harris, Anjanette P., Seckl, Jonathan R., Krugers, Harm, Joels, Marian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658081/ https://www.ncbi.nlm.nih.gov/pubmed/26600250 http://dx.doi.org/10.1371/journal.pone.0142012 |
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