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Glycosylation of Sodium/Iodide Symporter (NIS) Regulates Its Membrane Translocation and Radioiodine Uptake

PURPOSE: Human sodium/iodide symporter (hNIS) protein is a membrane glycoprotein that transports iodide ions into thyroid cells. The function of this membrane protein is closely regulated by post-translational glycosylation. In this study, we measured glycosylation-mediated changes in subcellular lo...

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Detalles Bibliográficos
Autores principales: Chung, Taemoon, Youn, Hyewon, Yeom, Chan Joo, Kang, Keon Wook, Chung, June-Key
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658105/
https://www.ncbi.nlm.nih.gov/pubmed/26599396
http://dx.doi.org/10.1371/journal.pone.0142984