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Red Queen Processes Drive Positive Selection on Major Histocompatibility Complex (MHC) Genes

Major Histocompatibility Complex (MHC) genes code for proteins involved in the incitation of the adaptive immune response in vertebrates, which is achieved through binding oligopeptides (antigens) of pathogenic origin. Across vertebrate species, substitutions of amino acids at sites responsible for...

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Detalles Bibliográficos
Autores principales: Ejsmond, Maciej Jan, Radwan, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658181/
https://www.ncbi.nlm.nih.gov/pubmed/26599213
http://dx.doi.org/10.1371/journal.pcbi.1004627