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Reassessment of MxiH subunit orientation and fold within native Shigella T3SS needles using surface labelling and solid-state NMR

T3SSs are essential virulence determinants of many Gram-negative bacteria, used to inject bacterial effectors of virulence into eukaryotic host cells. Their major extracellular portion, a ∼50 nm hollow, needle-like structure, is essential to host cell sensing and the conduit for effector secretion....

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Detalles Bibliográficos
Autores principales: Verasdonck, Joeri, Shen, Da-Kang, Treadgold, Alexander, Arthur, Christopher, Böckmann, Anja, Meier, Beat H., Blocker, Ariel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658334/
https://www.ncbi.nlm.nih.gov/pubmed/26439285
http://dx.doi.org/10.1016/j.jsb.2015.10.005